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NSE Mouse mAb
EM1066
規格: 價格:
50μL ¥1280.00
100μL ¥1980.00

Overview

Product name: NSE Mouse mAb
Reactivity: Human, Rat, Mouse
Alternative Names: ENO2, Enolase 2, enolase 2 (gamma, neuronal), Gamma enolase, Neural enolase, Neuron specific enolase
Source: Mouse
Dilutions: WB 1:2,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 47kDa
GeneID: 2026
Human Swiss-Prot No: P09104
Cellular localization: Cytoplasm. Cell membrane.
Background: Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.
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